phenobarbital sodium molecular weight - An Overview
phenobarbital sodium molecular weight - An Overview
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pentobarbital raises levels of vortioxetine by increasing metabolism. Modify Therapy/Observe Closely. Consider escalating the vortioxetine dose when coadministered with strong CYP inducers for >14 times; never to exceed 3 periods original vortioxetine dose.
Contraindicated (1)pentobarbital will reduce the extent or effect of doravirine by impacting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will lower the extent or effect of triazolam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
pentobarbital will decrease the extent or effect of linagliptin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe. Use of alternative treatment plans is strongly proposed when linagliptin will be to be administered with a CYP3A4 inducer
Phenytoin, sodium valproate, valproic acid: The effect of barbiturates around the metabolism of phenytoin seems to generally be variable. Some investigators report an accelerating effect, while others report no effect. As the effect of barbiturates on the metabolism of phenytoin will not be predictable, phenytoin and barbiturate blood stages should be monitored extra frequently if these drugs are specified concurrently.
pentobarbital increases toxicity of ifosfamide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe. CYP3A4 inducers may well boost the metabolism of ifosfamide to its Energetic alkylating metabolites.
Information and facts for that affected individual: Practitioners really should give the subsequent facts and instructions to patients obtaining barbiturates. The usage of barbiturates carries with it an related chance of psychological and/or Bodily dependence. The client really should be warned from growing the dose of your drug without consulting a health practitioner.
pentobarbital will lower the extent or effect of aripiprazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
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pentobarbital will decrease the level or effect of trazodone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
pentobarbital will lessen the level or effect of irinotecan more info by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
pentobarbital will lower the extent or effect of clarithromycin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Unidentified.
pentobarbital will lessen the extent or effect of diazepam buccal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on. Robust or average CYP3A4 inducers could maximize fee of diazepam elimination; consequently, efficacy of diazepam may very well be lowered.
fentanyl transdermal and pentobarbital equally enhance sedation. Stay clear of or Use Alternate Drug. Restrict use to clients for whom alternative cure choices are inadequate